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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1C All Species: 21.82
Human Site: S1040 Identified Species: 34.29
UniProt: O43896 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43896 NP_006603.2 1103 122947 S1040 S L D G G G R S R G A G S A Q
Chimpanzee Pan troglodytes XP_511296 1097 122335 S1034 S L D G G G R S R G A G S A Q
Rhesus Macaque Macaca mulatta XP_001117788 1214 134234 S1151 S L D G G G R S R G A G S A Q
Dog Lupus familis XP_546571 1191 131317 S1128 S L D G G G R S R G G G A A Q
Cat Felis silvestris
Mouse Mus musculus O35071 1100 122416 S1038 S L D G G S R S R G G G S T Q
Rat Rattus norvegicus O35787 1097 122315 S1035 S L D G G S R S R G G G S T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509769 1770 199343 R1438 N L A G W R P R G D S L I L E
Chicken Gallus gallus XP_417608 1757 197902 R1438 N L A G W R P R G D S L I L E
Frog Xenopus laevis Q91784 1226 138905 D1129 M D E G K H E D Q S L E S E N
Zebra Danio Brachydanio rerio XP_699380 1180 133432 Y1057 R N H G N R G Y G N W G N R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 K1446 D L M L K C L K L V Q G R Y T
Honey Bee Apis mellifera XP_397276 1682 191012 K1551 I S P V I A R K G Y L N V L E
Nematode Worm Caenorhab. elegans P23678 1584 179603 D1428 A S N D D I V D N L G G M K R
Sea Urchin Strong. purpuratus P46872 699 78679 D637 Q T P V A D K D K S L A Y G E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 A866 D R L E A A K A G S T R G L G
Conservation
Percent
Protein Identity: 100 99 89.6 87.7 N.A. 94.1 92.7 N.A. 38.1 38.7 23.9 60.4 N.A. 30.7 36.2 30.3 27.6
Protein Similarity: 100 99 89.9 89.3 N.A. 95.5 94.6 N.A. 48.6 48.4 42.3 71.8 N.A. 42.8 47.6 43.5 41
P-Site Identity: 100 100 100 86.6 N.A. 80 80 N.A. 13.3 13.3 13.3 20 N.A. 13.3 6.6 6.6 0
P-Site Similarity: 100 100 100 93.3 N.A. 80 80 N.A. 33.3 33.3 26.6 26.6 N.A. 13.3 13.3 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 26.5
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 43.7
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 14 0 14 14 0 7 0 0 20 7 7 27 0 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 7 40 7 7 7 0 20 0 14 0 0 0 0 0 % D
% Glu: 0 0 7 7 0 0 7 0 0 0 0 7 0 7 27 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 67 40 27 7 0 34 40 27 60 7 7 7 % G
% His: 0 0 7 0 0 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 7 7 0 0 0 0 0 0 14 0 0 % I
% Lys: 0 0 0 0 14 0 14 14 7 0 0 0 0 7 0 % K
% Leu: 0 60 7 7 0 0 7 0 7 7 20 14 0 27 0 % L
% Met: 7 0 7 0 0 0 0 0 0 0 0 0 7 0 0 % M
% Asn: 14 7 7 0 7 0 0 0 7 7 0 7 7 0 7 % N
% Pro: 0 0 14 0 0 0 14 0 0 0 0 0 0 0 0 % P
% Gln: 7 0 0 0 0 0 0 0 7 0 7 0 0 0 47 % Q
% Arg: 7 7 0 0 0 20 47 14 40 0 0 7 7 7 7 % R
% Ser: 40 14 0 0 0 14 0 40 0 20 14 0 40 0 0 % S
% Thr: 0 7 0 0 0 0 0 0 0 0 7 0 0 14 7 % T
% Val: 0 0 0 14 0 0 7 0 0 7 0 0 7 0 0 % V
% Trp: 0 0 0 0 14 0 0 0 0 0 7 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 7 0 0 7 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _